Most of the time, you can simply drag the App to the trash. That’s it. The secret is the app you just trashed is not one file but actually a special kind of folder with a collection of files inside. This collection of files make up an application.
Almost all apps keep track of your preferences settings in a .plist file. The .plist file is tiny in size (usually less than 4KB). If you want to reclaim every single bit of disc space, you can either go to ~/Library/Preferences to look for and delete it, or use AppZapper, AppDelete, CleanApp etc to automate the process. Most of the time we leave the .plist alone.
If an app comes with an Uninstaller, use it! An Uninstaller usually accompanies complex apps such as Microsoft Office and Adobe Creative Suite that spew support files, additional fonts, add-ons, custom extensions etc all over your harddisk.
So as you can see, uninstalling OS X’s apps is as simple as installing them! Yep, there’s no Registery nor DLL to get mad about.
 You can peek inside the special folder by right-clicking the app and select “Show Package Contents” from the pop-up menu.